Fig. 4
From: Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes
The effect of tick sialostatins on the production of IFN-β in plasmacytoid dendritic cells activated by Borrelia, TLR-7, and TLR-9 ligands. Plasmacytoid dendritic cells were activated with B. burgdorferi at MOI = 10 (a), imiquimod (2 μg/ml) (b) or CpG (50 nM) (c) in the presence or absence of sialostatins (both 3μM). Supernatants were collected 6 and 16 h after stimulation and analysed by ELISA assay