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Table 7 Therapeutic regimens used in cats affected by feline leishmaniosis

From: LeishVet update and recommendations on feline leishmaniosis

Drug and dosage

Duration

Number of treated cats

References

Allopurinol (10–15 mg/kg/12 h, 20 mg/kg/24 h, 25 mg/cat/12 h, 100 mg/cat/24 h) PO

6 months - 3 years

15

[14, 37, 50, 5456, 64, 65]

Meglumine antimoniate (20–50 mg/kg/24 h SC)

20–30 days

1

[59, 63]

Meglumine antimoniate (175 mg/cat/48 h IM)

55 days

1

[51]

Meglumine antimoniate (5 mg/kg/24 h SC) in combination with Ketoconazole (10 mg/kg/24 h PO)

3 cycles of 4 weeks, 10 days apart

1

[36]

Fluconazole (5 mg/kg/24 h PO)

60 days

1a

[37]

Spiramycin (150.000 IU/kg) and Metrodinazole (25 mg/kg) 24 h PO

35 days

1a

[37]

Itraconazole (50 mg/cat/24 h PO)

60 days

1a

[37]

  1. SC: subcutaneous; IM: intamuscular; PO: per os a a same cat was treated with the three different therapeutic regimens at subsequent times