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Fig. 1 | Parasites & Vectors

Fig. 1

From: Molecular insights into a tetraspanin in the hydatid tapeworm Echinococcus granulosus

Fig. 1

Phylogenetic analysis and the cysteine pattern in Eg-TSP1. a The hypervariable region of tetraspanins was aligned and they were grouped according to their cysteine patterns. The conserved cysteine-motif is summarized and the canonical topologies of disulfide bonds are shown above the alignment. b A phylogenetic tree was constructed based on the amino acid sequences of parasite and human tetraspanins using the Bayesian method. Three major monophyletic subfamilies were detected, including the CD family, the CD63 family, and the Uroplakin family. Eg, E. granulosus; Em, E. multilocularis; Sm, S. mansoni; Sj, S. japonicum; Sh, S. haematobium; Ts, T. solium; Hs, Homo species. GenBank accession numbers: Em-TSP 1–7 [FJ384717, FJ384718, FJ384719, FJ384720, FJ384721, FJ384722 and FJ384716, respectively]; Sj-TSP 1–6 [AAW26928, AAW24822, AAW24863, AAP05954, AAW27174 and AAW26326, respectively]; Sm-TSP-1 [AF521093]; Sm-TSP-2 [AF521091]; Sm23 [M34453]; Sj23 [M63706]; Sh23 [U23771]; Sm25 [AF028730]; Sj25 [U77941]; Ts-T24 [AY211879] and Human-TSP1 [NP_005718.2]

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