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Table 1 Distribution and relative staining intensity for Nras/let-60 in untreated and ivermectin-treated O. volvulus adult female worms

From: A histochemical study of the Nras/let-60 activity in filarial nematodes

Anatomical location Untreated parasites Ivermectin treated parasites
  Uniformitya Intensityb Uniformitya Intensityb
Hypodermis 3 3 2 1
Uterine epithelium 3 3 1 1
Intestinal epithelium 2 2 2 1
Oocytes 3 3 3 1
Morulae 3 3 NP NP
Coiled mff 3 3 NP NP
Mature mff 3 3 NP NP
Spermatocytes 3 3 2 1
Spermatozoa 1 1 1 1
  1. aUniformity score: Based on the overall distribution of the staining throughout the particular anatomical structure. Range: 3 = predominantly present; 2 = moderately present; 1 = limited presence; 0 = no staining present, NP = stage not present in worm
  2. bIntensity Score: Based on the overall intensity observed in all positive locations compared to human tissue control in the same section. Range: 0 = no staining; 1 = weak staining; 2 = moderate staining; 3 = strong staining