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Table I Putative ubiquitin-specific proteases in S. mansoni

From: Ubiquitin-specific proteases are differentially expressed throughout the Schistosoma mansoni life cycle

USP

S. mansoni putative orthologs

KEGG Orthology Entry (KO)

KEGG Orthology name

Length (aa)

Domain and Pfam number

Orthologue length (aa) in Homo sapiens

Pfam e-value

USP2

Smp_212390

K11833

USP2_21

563

UCH (PF00443) (171)

605

3.1e-66

USP5

Smp_069960

K11836

USP5_13, UBP14

916

zf-UBP

855

2.6e-16 1.4e-40

     

UCH (341) UBA

 

1.6e-08

USP7

Smp_089180

K11838

USP7, UBP15

1412

MATH

1102

3.1e-12

     

UCH (257)

 

7.4e-52

USP8

Smp_152000

K11839

USP8, UBP5

1027

IPPT

1118

1.7e-16

     

UCH (685)

 

6.5e-69

USP9x

Smp_153690

K11840

USP9_24

811

UCH

918

9.7e-22

USP10

Smp_005280

K11841

USP10, UBP3

597

UCH (91)

802

5.9e-31

USP14

Smp_084740

K11843

USP14, UBP6

178

UCH (52)

494

3.9e-42

USP15

Smp_128770

K11835

USP4_11_15,

945

DUSP

951

3.8e-14

   

UBP12

 

UCH (296)

 

3.4e-78

USP16

Smp_074200.1

K11844

USP16_45

622

UCH (44)

823

4.9e-30

USP20

Smp_021300

K11848

USP20_33

881

UCH (34)

914

6.1e-66

     

DUSP

 

1.5e-12

USP22

Smp_074400

K11366

USP22_27_51, UBP8

489

UCH (181)

525

3.5e-52

USP24

Smp_198740

K11840

USP9_24

2235

UCH (229)

2620

4e-17

USP30

Smp_122960.1

K11851

USP30

595

UCH (58)

517

1.4e-21

USP36-42

Smp_046430

K11855

USP36_42

799

UCH (178)

1123

2e-49

USP39

Smp_017890

K12847

USP39, SAD1

577

zf-UBP

565

1.5e-12

     

UCH

 

7.5e-37

USP46

Smp_000710

K11842

USP12_46

414

UCH (47)

366

8e-67

USP48

Smp_196290

K11858

USP48

1281

UCH (95)

1035

2.3e-12

USP49-44

Smp_123630

K11834

USP44_49

823

zf-UBP

640

2.7e-18

     

UCH (201)

 

1.1e-63

  1. All enzymes are classified as ubiquitin thioesterase