| Day 2 | Day 30 | Day 58 | Day 86 | Day 93 | Day 100 | Day 107 | Day 114 | Day 122 |
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Treatment1
| Mean # of fleas2,3
| % control4
| Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control | Mean # of fleas | % control |
Controls | 93.9 | | 75.7 | | 78.6 | | 47.2 | | 55.6 | | 62.3 | | 54.9 | | 54.6 | | 52.0 | |
Fluralaner | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 |
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112 dogs were used in this study. The 6 dogs in each control group received no treatment. The 6 dogs in the fluralaner group were administered an oral chewable tablet once on Day 0
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2Each dog was infested with approximately 200 adult Ctenocephalides felis felis from the KS1 strain on days −2, 7, 28, 56, 84, 91, 105, 112 and 120 post-treatment
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3Geometric mean # of live fleas recovered from dogs per treatment group
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4 % control = ((geometric mean count control -geometric mean count treatment)/ geometric mean count treatment)) × 100
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ageometric mean of treatment group was significantly different from control (P <0.001)