| Day 2 | Day 30 | Day 58 | Day 86 | Day 93 | Day 100 | Day 107 | Day 114 | Day 122 |
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Treatment1
| Mean # of eggs2,3
| % control4
| Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control | Mean # of eggs | % control |
Controls | 171.7 | | 128.9 | | 83.9 | | 67.1 | | 87.4 | | 53.8 | | 64.4 | | 26.7 | | 67.4 | |
Fluralaner | 0.2a
| 99.9 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 | 0.0a
| 100 |
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112 dogs were used in this study. The 6 dogs in each control group received no treatment. The 6 dogs in the fluralaner group were administered an oral chewable tablet once on Day 0
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2Each dog was infested with approximately 200 adult Ctenocephalides felis felis from the KS1 strain on days −2, 7, 28, 56, 84, 91, 105, 112 and 120 post-treatment, flea eggs were collected 48 h post-treatment or post-infestation during a 3-h collection period
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3Geometric mean # of eggs recovered from dogs per treatment group
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4 % control = ((geometric mean count control -geometric mean count treatment)/ geometric mean count treatment)) x 100
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ageometric mean of treatment group was significantly different from control (P ≤0.001)