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Table 3 The prevalence and intensity of Schistosoma haematobium infections in children from six villages in the Niakhar study area in Central Senegal at baseline, 5 weeks post treatment and reinfection levels at 2 to 3 months after draining of ponds and backwater, relative to gender and age

From: Efficacy of praziquantel against urinary schistosomiasis and reinfection in Senegalese school children where there is a single well-defined transmission period

Characteristics S. haematobium infection
   Gender    Age   
Variables Female Male P-value 5 - 7 years 8 - 10 years 11 - 15 years P-value
Baseline (June 2011)
No. of children infected/examined 91/142 150/187   88/141 85/105 68/83  
Prevalence (95 % CI) 64.1 % (55.9-71.5) 80.2 % (73.9-85.3) 0.001 62.4 % (54.2-69.9) 80.9 % (72.4-87.3) 81.9 % (62.3-88.7) 0.001
Numbers of infected subject treated with PZQ 91 146   88 83 66  
GM egg count/10 ml of urine (95 % CI) 177.0 (123.4-253.8) 544.1 (421.4-702.6) 0.001 238.9 (164.4-347.3) 455.6 (313–662.9) 438.7 (299.1-643.3) <0.001
Treatment (August 2011)
Follow-up efficacy of PZQ 5 weeks post treatment (in September 2011)
No. of children infected/examined 3/142 12/183   6/141 8/103 1/81  
Prevalence (95 % CI) 2.1 % (0.7-6) 6.5 % (3.7-10.9) 0.080 4.2 % (1.9-8.9) 7.7 % (3.9-14.4) 1.2 % (0.2-6.7) 0.200
No. of infected treated examined 91 146   88 83 66  
No of children cured (CR in %) 88 (96.7 %) 134 (91.8 %) 0.7 82 (93.2 %) 76 (91.7 %) 64 (96.9 %) 0.5
GM egg count/10 ml of urine (95 % CI) 15.7 (3.7-65.4) 55.8 (25.5-112.9) 0.06 26.5 (8–87.7) 67.0 (26.9-166.5) 25.0 0.109
ERR in % 91.1 % 89.7 % 0.99 88.9 % 85.3 % 94.3 % 0.99
Reinfection after treatment (September to November 2011)
Follow-up reinfection 2 to 3 months after transmission period in February and March 2012
No. of children infected/examined 11/142 34/183   22/141 14/103 9//81  
Prevalence (95 % CI) 7.7 % (4.3-13.3) 18.6 % (13.1-24.8) 0.010 15.6 % (10.5-22.5) 13.6 % (8.2-21.5) 11.1 % (5.9-19.8) 0.486
GM egg count/10 ml of urine (95 % CI) 37.4 (37.4-12.38) 52.4 (25.2-109.2) 0.012 73.1 (31.8-168.3) 27.8 (9.4-82.4) 38.6 (5.6-263.7) 0.307
No. Of children re-infected/surveyed 8/139 22/173   16/135 8/96 6/81  
Reinfection rate (95 % CI) 5.7 % (2.9-10.9) 12.7 % (8.5-18.5) 0.001 11.8 % (7.4-18.4) 8.3 % (4.3-15.6) 7.4 % (3.4-15.2) 0.400