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Fig. 10 | Parasites & Vectors

Fig. 10

From: Anopheles stephensi p38 MAPK signaling regulates innate immunity and bioenergetics during Plasmodium falciparum infection

Fig. 10

Inhibition of AsP38 MAPK altered pyruvate and lactate concentrations in the A. stephensi midgut. A. stephensi were fed a P. falciparum-infected blood meal supplemented with either 10 μM BIRB796 or an equivalent volume of DMSO and 300 midguts/group were collected at 0, 48, and 72 h post-feeding to determine pyruvate and lactate levels. Graphs represent means ± SEMs of 3 independent measurements. Statistical analysis was performed by one-way ANOVA, followed by Bonferroni’s post-test for multiple comparisons between treatments (BIRB796) and controls (DMSO); significant p-values are shown

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