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Table 4 Cytokine profiles corresponding to human PBMCs cultured in the presence of phytoecdysteroids or concanavalin A

From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

  Cytokine levels [pg/mL]
PBMCs control α-ecdysone 20-hydroxyecdysone ConA
IFN-γ
0 2 10 20 2 20 100 2.5
A. mean 126.75 132.52 129.92 125.68 127.04 124.58 131.26 2 661.02*
N = 52 SD 106.20 121.25 114.94 114.31 123.67 116.29 127.42 1197.77
  median 118.26 127.32 120.45 121.71 120.44 122.88 212.62 2 238.19
B. mean 11.96 7.85 10.86 11.23 7.12 7.74 9.96 1003.35*
N = 8 SD 10.16 1.94 4.32 4.25 1.57 0.97 5.04 414.06
  median 7.21 7.97 9.32 9.63 7.07 7.75 7.51 107.77
  IL-10
A. mean 240.76 255.75 297.50 311.00 255.81 296.75 301.58 2758.74*
N = 48 SD 206.93 202.64 236.93 253.40 183.88 183.35 243.97 1075.34
  median 143.54 209.02 199.84 286.51 254.64 286.36 327.35 2849.68
B. mean 13.12 8.56 8.66 7.23 9.89 8.93 11.30 606.68*
N = 9 SD 3.09 1.39 2.25 1.50 2.43 3.95 7.10 196.97
  median 13.00 8.79 8.79 7.60 10.57 7.90 8.79 574.96
  1. PBMCs were derived from individuals who responded (A) or did not respond (B) to phytoecdysteroids. The statistically significant differences (p < 0.05) were labeled with an asterisk (*)