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Table 4 Cytokine profiles corresponding to human PBMCs cultured in the presence of phytoecdysteroids or concanavalin A

From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

 

Cytokine levels [pg/mL]

PBMCs

control

α-ecdysone

20-hydroxyecdysone

ConA

IFN-γ

0

2

10

20

2

20

100

2.5

A.

mean

126.75

132.52

129.92

125.68

127.04

124.58

131.26

2 661.02*

N = 52

SD

106.20

121.25

114.94

114.31

123.67

116.29

127.42

1197.77

 

median

118.26

127.32

120.45

121.71

120.44

122.88

212.62

2 238.19

B.

mean

11.96

7.85

10.86

11.23

7.12

7.74

9.96

1003.35*

N = 8

SD

10.16

1.94

4.32

4.25

1.57

0.97

5.04

414.06

 

median

7.21

7.97

9.32

9.63

7.07

7.75

7.51

107.77

 

IL-10

A.

mean

240.76

255.75

297.50

311.00

255.81

296.75

301.58

2758.74*

N = 48

SD

206.93

202.64

236.93

253.40

183.88

183.35

243.97

1075.34

 

median

143.54

209.02

199.84

286.51

254.64

286.36

327.35

2849.68

B.

mean

13.12

8.56

8.66

7.23

9.89

8.93

11.30

606.68*

N = 9

SD

3.09

1.39

2.25

1.50

2.43

3.95

7.10

196.97

 

median

13.00

8.79

8.79

7.60

10.57

7.90

8.79

574.96

  1. PBMCs were derived from individuals who responded (A) or did not respond (B) to phytoecdysteroids. The statistically significant differences (p < 0.05) were labeled with an asterisk (*)