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Table 5 Cytokine profiles corresponding to human PBMCs infected by T. gondii and incubated with phytoecdysteroids or concanavalin A

From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

 

Cytokine levels [pg/mL]

PBMCs and Toxoplasma

control

α-ecdysone

20-hydroxyecdysone

ConA

IFN-γ

0

2

10

20

2

20

100

2.5

A.

mean

579.94

668.42

644.86

601.85

612.61

603.78

615.51

1040.90*

N = 49

SD

552.02

541.49

515.38

500.54

540.02

524.31

522.29

543.24

 

median

362.98

441.04

448.27

494.70

464.31

422.97

492.39

941.43

B.

mean

58.30

91.36

79.17

74.69

67.42

64.34

75.88

171.39*

N = 10

SD

35.80

65.93

50.10

46.09

35.78

40.41

50.66

68.67

 

median

61.19

68.31

71.24

83.38

65.14

59.40

75.96

163.96

 

IL-10

A.

mean

622.90

542.24

616.43

706.24

608.92

660.99

623.21

728.45

N = 46

SD

309.04

338.16

292.83

350.71

311.57

309.01

328.14

589.63

 

median

521.62

455.37

491.01

566.36

562.35

523.13

500.08

681.18

B.

mean

68.94

46.73

65.46

81.36

51.35

57.03

62.39

88.98

N = 12

SD

51.28

33.14

44.68

46.89

31.61

41.42

45.79

51.47

 

median

41.48

38.49

40.54

56.04

40.38

37.97

39.59

68.94

  1. PBMCs were derived from individuals who responded (A) or did not respond (B) to phytoecdysteroids. The statistically significant differences (p < 0.05) were labeled with an asterisk (*)