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Table 5 Cytokine profiles corresponding to human PBMCs infected by T. gondii and incubated with phytoecdysteroids or concanavalin A

From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells

  Cytokine levels [pg/mL]
PBMCs and Toxoplasma control α-ecdysone 20-hydroxyecdysone ConA
IFN-γ
0 2 10 20 2 20 100 2.5
A. mean 579.94 668.42 644.86 601.85 612.61 603.78 615.51 1040.90*
N = 49 SD 552.02 541.49 515.38 500.54 540.02 524.31 522.29 543.24
  median 362.98 441.04 448.27 494.70 464.31 422.97 492.39 941.43
B. mean 58.30 91.36 79.17 74.69 67.42 64.34 75.88 171.39*
N = 10 SD 35.80 65.93 50.10 46.09 35.78 40.41 50.66 68.67
  median 61.19 68.31 71.24 83.38 65.14 59.40 75.96 163.96
  IL-10
A. mean 622.90 542.24 616.43 706.24 608.92 660.99 623.21 728.45
N = 46 SD 309.04 338.16 292.83 350.71 311.57 309.01 328.14 589.63
  median 521.62 455.37 491.01 566.36 562.35 523.13 500.08 681.18
B. mean 68.94 46.73 65.46 81.36 51.35 57.03 62.39 88.98
N = 12 SD 51.28 33.14 44.68 46.89 31.61 41.42 45.79 51.47
  median 41.48 38.49 40.54 56.04 40.38 37.97 39.59 68.94
  1. PBMCs were derived from individuals who responded (A) or did not respond (B) to phytoecdysteroids. The statistically significant differences (p < 0.05) were labeled with an asterisk (*)