Table 6 Cytokine profiles corresponding to the mice splenocytes cultivated in the presence of phytoecdysteroids and concanavalin A
From: Phytoecdysteroids as modulators of the Toxoplasma gondii growth rate in human and mouse cells
Cytokine levels [pg/mL] | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Splenocytes | control | α-ecdysone | 20-hydroxyecdysone | ConA | |||||
IFN-γ | |||||||||
0 | 2 | 10 | 20 | 2 | 20 | 100 | 2.5 | ||
BALB/c | mean | 752.33 | 606.89 | 552.24 | 667.61 | 716.58 | 709.40 | 663.52 | 1997.97* |
N = 12 | SD | 634.53 | 423.51 | 438.02 | 599.92 | 452.11 | 568.89 | 409.02 | 369.25 |
negative | median | 48.28 | 566.79 | 498.71 | 632.57 | 666.49 | 657.71 | 565.57 | 1857.23 |
BALB/c | mean | 1735.99 | 1000.17 | 1168.71 | 1057.95 | 1540.23 | 1661.91 | 1560.54 | 4307.02* |
N = 9 | SD | 714.81 | 687.62 | 843.80 | 901.84 | 572.05 | 604.58 | 633.65 | 82.08 |
positive | median | 1848.28 | 878.07 | 976.23 | 819.85 | 1385.37 | 1485.31 | 1439.19 | 4292.66 |
IL-10 | |||||||||
BALB/c | mean | 19.49 | 20.84 | 18.87 | 19.60 | 21.39 | 19.20 | 20.54 | 1987.46* |
N = 12 | SD | 9.08 | 13.12 | 7.80 | 10.45 | 8.12 | 8.85 | 9.55 | 340.02 |
negative | median | 16.30 | 18.58 | 16.08 | 17.56 | 19.86 | 17.48 | 18.96 | 1883.19 |
BALB/c | mean | 1344.07 | 1351.45 | 1385.59 | 1426.28 | 1550.71 | 1390.64 | 1437.98 | 2531.09* |
N = 9 | SD | 583.19 | 543.89 | 550.90 | 522.69 | 506.47 | 494.77 | 521.20 | 661.58 |
positive | median | 972.59 | 975.12 | 1006.89 | 1084.91 | 1228.71 | 1158.47 | 1079.78 | 2878.76 |
IL-2 | |||||||||
BALB/c | mean | 11.58 | 9.85 | 9.04 | 9.64 | 9.54 | 10.63 | 9.71 | 159.12* |
N = 10 | SD | 9.76 | 2,55 | 3.32 | 3.21 | 3.82 | 3.79 | 3.23 | 30.02 |
negative | median | 10.03 | 8.01 | 7.96 | 7.86 | 7.32 | 8.56 | 8.56 | 143.45 |
BALB/c | mean | 16.22 | 21.82 | 15.88 | 19.91 | 19.31 | 19.80 | 20.98 | 276.97* |
N = 10 | SD | 10.25 | 11.48 | 8.83 | 13.63 | 15.55 | 12.89 | 13.42 | 42.75 |
positive | median | 15.25 | 17.77 | 14.25 | 16.45 | 13.55 | 15.50 | 19.05 | 290.12 |