Skip to main content

Table 1 Summary of pharmacokinetic parameters in dogs following oral administration of advantus™ chewable tablets

From: Development of advantus™(imidacloprid) soft chewable tablets for the treatment of Ctenocephalides felis infestations on dogs

Dog ID

Tmax (h)

Cmax (ng/mL)

AUC last (h*ng/mL)

Half-life (h)

4153

1

654

3075.4

3.01

4181

1

557

1938.61

1.62

4374

1

764

2846.85

2.16

4386

0.5

693

2101.38

2.06

4140

4

512

3093.1

2.27

4175

1

812

2756.6

2.09

4182

1

777

2866.6

2.41

4383

1

751

2245.5

2.1

Mean

1.31

690

2615.5

2.2