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Table 1 Summary of pharmacokinetic parameters in dogs following oral administration of advantus™ chewable tablets

From: Development of advantus™(imidacloprid) soft chewable tablets for the treatment of Ctenocephalides felis infestations on dogs

Dog ID Tmax (h) Cmax (ng/mL) AUC last (h*ng/mL) Half-life (h)
4153 1 654 3075.4 3.01
4181 1 557 1938.61 1.62
4374 1 764 2846.85 2.16
4386 0.5 693 2101.38 2.06
4140 4 512 3093.1 2.27
4175 1 812 2756.6 2.09
4182 1 777 2866.6 2.41
4383 1 751 2245.5 2.1
Mean 1.31 690 2615.5 2.2