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Table 2 Confirmation of 0.75 mg/kgbody weight as the dose of advantus™ chewable tablet

From: Development of advantus™(imidacloprid) soft chewable tablets for the treatment of Ctenocephalides felis infestations on dogs

Time1 Treatment Variable N Mean Std Dev Minimum Maximum Efficacy (%) p-value
8 IVP2 Count 8 3.00 6.55 0.00 19.00   
LogCount 8 0.31 0.46 0.00 1.30 98.63 <.00014
CVP3 Count 8 85.13 27.37 18.00 100.00
LogCount 8 1.89 0.25 1.28 2.00
12 IVP Count 8 0.13 0.35 0.00 1.00 99.90 <.00014
LogCount 8 0.04 0.11 0.00 0.30
CVP Count 8 89.75 7.32 78.00 98.00
LogCount 8 1.96 0.04 1.90 2.00
24 IVP Count 8 0.00 0.00 0.00 0.00 100.00 <.00014
LogCount 8 0.00 0.00 0.00 0.00
CVP Count 8 91.13 6.62 82.00 100.00
LogCount 8 1.96 0.03 1.92 2.00
  1. 1Time in hours post-treatment when efficacy was determined
  2. 2IVP is the advantus™ chewable tablets as the investigational veterinary product
  3. 3CVP is the placebo chewable tablets as control veterinary product
  4. 4Statistically significant at p < 0.01