Development of advantus™(imidacloprid) soft chewable tablets for the treatment of Ctenocephalides felis infestations on dogs

Table 3 Knockdown and Speed of kill efficacy of advantus™ chewable tablet administered at 0.75 mg/kg BW

Time¹	Treatment	Variable	N	Mean	Std Dev	Minimum	Maximum	Efficacy(%)	p-value
0.5	Treated	Count	6	79.00	29.37	21.00	100.00	24.6	0.2719
	Treated	LogCount	6	1.86	0.25	1.34	2.00
	Control	Count	6	94.33	4.63	88.00	100.00
	Control	LogCount	6	1.98	0.02	1.95	2.00
1	Treated	Count	6	64.33	12.99	51.00	85.00	29.7	0.0073²
	Treated	LogCount	6	1.81	0.08	1.72	1.93
	Control	Count	6	91.00	13.56	65.00	100.00
	Control	LogCount	6	1.96	0.07	1.82	2.00
4	Treated	Count	6	3.17	1.60	2.00	6.00	96.6	<0.0001²
	Treated	LogCount	6	0.60	0.15	0.48	0.85
	Control	Count	6	85.83	7.22	77.00	95.00
	Control	LogCount	6	1.94	0.04	1.89	1.98
24	Treated	Count	6	0.17	0.41	0.00	1.00	99.9	<0.0001²
	Treated	LogCount	6	0.05	0.12	0.00	0.30
	Control	Count	6	94.83	5.27	85.00	99.00
	Control	LogCount	6	1.98	0.02	1.93	2.00

ISSN: 1756-3305