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Table 3 Knockdown and Speed of kill efficacy of advantus™ chewable tablet administered at 0.75 mg/kg BW

From: Development of advantus™(imidacloprid) soft chewable tablets for the treatment of Ctenocephalides felis infestations on dogs

Time1 Treatment Variable N Mean Std Dev Minimum Maximum Efficacy(%) p-value
0.5 Treated Count 6 79.00 29.37 21.00 100.00 24.6 0.2719
LogCount 6 1.86 0.25 1.34 2.00
Control Count 6 94.33 4.63 88.00 100.00
LogCount 6 1.98 0.02 1.95 2.00
1 Treated Count 6 64.33 12.99 51.00 85.00 29.7 0.00732
LogCount 6 1.81 0.08 1.72 1.93
Control Count 6 91.00 13.56 65.00 100.00
LogCount 6 1.96 0.07 1.82 2.00
4 Treated Count 6 3.17 1.60 2.00 6.00 96.6 <0.00012
LogCount 6 0.60 0.15 0.48 0.85
Control Count 6 85.83 7.22 77.00 95.00
LogCount 6 1.94 0.04 1.89 1.98
24 Treated Count 6 0.17 0.41 0.00 1.00 99.9 <0.00012
LogCount 6 0.05 0.12 0.00 0.30
Control Count 6 94.83 5.27 85.00 99.00
LogCount 6 1.98 0.02 1.93 2.00
  1. 1Time in hours post-treatment when efficacy was determined
  2. 2Statistically significant