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Fig. 4 | Parasites & Vectors

Fig. 4

From: T. gondii rhoptry protein ROP18 induces apoptosis of neural cells via endoplasmic reticulum stress pathway

Fig. 4

Western blotting analyses of inhibitors on caspase-12, caspase-3 and CHOP expression levels in N2a cells. After the N2a cells were treated with or without ZAF, they were infected with ROP18-RH or RH tachyzoites at an m.o.i of ~3 for 24 h. a The presented figures are from a representative study and the quantitative data were expressed as mean ± SD on different assays (n = 3). The N2a cells without the infection of tachyzoites or only pretreated with ZAF were used as controls. ROP18-RH + ZAF or RH + ZAF stands for the N2a cells pretreated with ZAF, and then infected with either ROP18-RH or RH tachyzoites. b The quantitative data of a panel. The experiments were repeated three times (n = 3). # P < 0.001 vs. control; * P < 0.05 vs. RH group; & P < 0.05 vs. ROP18-RH group

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