Skip to main content

Table 5 Number (%) of participants by characteristics of local reaction under the OCP and LTS-2 patches

From: Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Characteristics OCP-patch (N = 30) LTS-2 patch (N = 30)
Definition of reaction At 24 h At 30 h At 24 h At 30 h
 None 3 (10.0) 2 (6.7) 5 (16.7) 0
Oedema under the patch (any score) NA NA 25 (83.3) 30 (100)
 100 % of area oedematous (score 3) NA NA 17 (56.7) 27 (90.0)
  > 50 % of area oedematous (score 2) NA NA 4 (13.3) 3 (10.0)
  < 50 % of area oedematous (score 1) NA NA 4 (13.3) 0
 0 % of area oedematous (score 0) NA NA 5 (15.7) 0
 All reactions 27 (90.0) 28 (93.3) 25 (83.3) 30 (100)
  Very easily visible reaction 18 (60.0) 24 (80.0) 22 (73. 19 (63.3)
  Easily visible reaction 2 (6.7) 3 (10.0) 0 1 (3.3)
  Attentive visual inspection required 7 (23.3) 1 (3.3) 3 (10.0) 10 (33.3)
Character of papules     
 None 3 (10.0) 2 (6.7) 5 (16.7) 0
 Vague 4 (13.3) 1 (3.3) 3 (10.0) 0
 Pinheads 16 (53.3) 16 (53.3) 0 0
 Pinpoints 7 (23.3) 11 (36.7) 19 (63.3) 29 (96.7)
 Urticariform 0 0 3 (10.0) 1 (3.3)
Extension beyond patch area 2 (6.7) 8 (26.7) 0 0