Diagnosis of O. volvulus infection via skin exposure to diethylcarbamazine: clinical evaluation of a transdermal delivery technology-based patch

Table 7 Proportion of subjects with local reaction by skin mf level measured 1 cm away from patch application area before application and by mean skin mf level across all skin snips taken

OCP-patch						LTS-2 patch
Skin 1 cm from patch area pre application		% of subjects by score at 24 h		% of subjects by score at 30 h		Skin 1 cm from patch area pre application		% of subjects by score at 24 h		% of subjects by score at 30 h
mf/mg	N	1	≥2	1	≥2	mf/mg	N	1	≥2	1	≥2
<1.0	5	20.0	40	0	100	<1.0	7	28.6	57.1	0	100
1–5	10	40.0	60	0	90.0	1–5	9	0	77.8	0	100
>5	15	13.3	80	0	93.3	>5	14	14.3	71.4	0	100
All snips						All snips
mf/mg	N	1	≥2	1	≥2	mf/mg	N	1	≥2	1	≥2
<1.0	5	40.0	40.0	0	100	<1.0	5	20	80	0	100
1–5	8	37.5	50.0	0	100	1–5	8	12.5	71.4	0	100
>5	17	11.8	82.4	0	88.3	>5	17	11.8	70.6	0	100
Any	30	23.3	66.7	0	93.3	Any	30	13.3	70.0	0	100
		≥1		≥1				≥1		≥1
Any	30	90		93.3		Any	30	83.3		100

ISSN: 1756-3305