Skip to main content

Table 2 Ivermectin pharmacokinetic parameters in dogs following oral administration (0.3 mg/kg BW) alone or concurrently with fluralaner (56 mg/kg BW)

From: Plasma pharmacokinetic profile of fluralaner (Bravecto™) and ivermectin following concurrent administration to dogs

Parameter Unit Ivermectin Ivermectin plus Fluralaner P-value
Mean ± SD Mean ± SD
Cmax (ng/mL) 92.70 ± 26.77 80.52 ± 21.41 0.2465
tmax (day) 0.29 ± 0.10 0.31 ± 0.11 0.7269
AUC (day*ng/mL) 141.96 ± 27.23 134.26 ± 37.99 0.5073
(days) 2.07 ± 0.71 1.84 ± 0.42 0.4888
  1. SD standard deviation