Fig. 2From: Possible changes in the transmissibility of trachoma following MDA and transmission reduction: implications for the GET2020 goalsAnnual MDA treatments in three endemic settings, impact and rebound Each endemic setting is subjected to 3 and 10 annual rounds of simulated MDA (with coverage and efficacy detailed in the main text, Methods). Infection is essentially eliminated following 3 and 10 rounds in the hypoendemic setting (a and d), but remains at a detectable level throughout the MDA programme in both meso (b and e)and hyperendemic (c and f) settings. The rate of rebound of infection increases over time in all settings but, once MDA ceases, its magnitude results in a large overshoot of infection prevalence beyond its baseline level in the hypo–and mesoendemic settingsBack to article page