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Table 2 Sensitivity analyses of model projections to changes in the values of key parameters

From: What impact will the achievement of the current World Health Organisation targets for anthelmintic treatment coverage in children have on the intensity of soil transmitted helminth infections?

  Pre-SAC SAC Adults Overall population
Ascaris     
 Fitted parameters (see Table 1) 71 75 63 70
 Higher and lower transmission setting (R0 + 1.0, −0.5) 35, 99 45, 99 24, 99 36, 99
 Coverage level achieved in 2020 (60 %, 90 %) 59, 82 64, 85 51, 73 58,80
 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %) 83, 48 85, 56 76, 37 82, 45
Trichuris     
 Fitted parameters (see Table 1) 43 48 40 44
 Higher and lower transmission setting (R0 + 1.0, −0.5) 24, 80 31, 81 20, 77 24, 79
 Coverage level achieved in 2020 (60 %, 90 %) 37, 49 42, 54 34, 45 38, 49
 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %) 45, 38 50, 43 43, 32 46, 37
Hookworm     
 Fitted parameters (see Table 1) 39 50 16 22
 Higher and lower transmission setting (R0 + 1.0, −0.5) 36, 43 48, 54 12, 21 19, 27
 Coverage level achieved in 2020 (60 %, 90 %) 34, 43 45, 55 14, 17 20, 24
 The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β2 and β3 + 50 %, −50 %) 45, 33 55, 45 24, 6 32, 10
  1. The numerical values record the percentage reduction in the predicted mean intensity of infection in each age group from a rising treatment coverage to 75 % in 2020 as compared to baseline in 2003. The default parameters are in Table 1