What impact will the achievement of the current World Health Organisation targets for anthelmintic treatment coverage in children have on the intensity of soil transmitted helminth infections?

Table 2 Sensitivity analyses of model projections to changes in the values of key parameters

	Pre-SAC	SAC	Adults	Overall population
Ascaris
Fitted parameters (see Table 1)	71	75	63	70
Higher and lower transmission setting (R₀ + 1.0, −0.5)	35, 99	45, 99	24, 99	36, 99
Coverage level achieved in 2020 (60 %, 90 %)	59, 82	64, 85	51, 73	58,80
The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β₂ and β₃ + 50 %, −50 %)	83, 48	85, 56	76, 37	82, 45
Trichuris
Fitted parameters (see Table 1)	43	48	40	44
Higher and lower transmission setting (R₀ + 1.0, −0.5)	24, 80	31, 81	20, 77	24, 79
Coverage level achieved in 2020 (60 %, 90 %)	37, 49	42, 54	34, 45	38, 49
The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β₂ and β₃ + 50 %, −50 %)	45, 38	50, 43	43, 32	46, 37
Hookworm
Fitted parameters (see Table 1)	39	50	16	22
Higher and lower transmission setting (R₀ + 1.0, −0.5)	36, 43	48, 54	12, 21	19, 27
Coverage level achieved in 2020 (60 %, 90 %)	34, 43	45, 55	14, 17	20, 24
The degree of exposure and contribution of Pre-SAC and SAC to the infectious reservoir (β₂ and β₃ + 50 %, −50 %)	45, 33	55, 45	24, 6	32, 10

The numerical values record the percentage reduction in the predicted mean intensity of infection in each age group from a rising treatment coverage to 75 % in 2020 as compared to baseline in 2003. The default parameters are in Table 1

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