Table 1 Summary of parameter values used to inform the model

n

Size of population in simulation

1000 unless otherwise stated

N/A

λ

Number of bites per mosquito

10 per month

[37, 38]

V/H

Ratio of number of vectors to hosts

Fitted to data

N/A

α _max

Age at which exposure to mosquitoes reaches its maximum level

20.0

[12]

ψ ₁

Proportion of L3 leaving mosquito per bite

0.414

[39]

ψ ₂

Proportion of L3 leaving mosquito that enter host

0.32

[40]

s ₂

Proportion of L3 entering host that develop into adult worms

0.00275

[7, 41]

μ

Death rate of adult worms

0.0104 per month

[42]

α

Production rate of Mf per worm

0.2 per month

[39]

γ

Death rate of Mf

0.1 per month

[39, 43]

ɡ

Proportion of mosquitoes which pick up infection when biting an infected host

0.37

[45]

σ

Death rate of mosquitoes

5 per month

[40]

k

Aggregation parameter of individual exposure to mosquitoes

Fitted to data

[23, 24]

h(a)

Parameter to adjust rate at which individuals of age α are bitten

Linear from 0 to 10, with maximum of 1

[7]

χ ₁

Proportion of Mf killed for an individual MDA round using ALB & DEC

0.95

[46, 47]

κ ₁

Proportion of adult worm permanently sterlised during MDA round using ALB & DEC

0.55

[46, 47]

ρ

Systematic adherence of MDA

Varied

N/A

p _C

Coverage of MDA

Varied

N/A

p _N

Coverage of LLIN

Varied

N/A

ρ _BC

Correlation between bite exposure and adherence to MDA

Varied

N/A

ρ _CN

Correlation between adherence to MDA & LLIN

Varied

N/A