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Table 1 Summary of parameter values used to inform the model

From: Modelling strategies to break transmission of lymphatic filariasis - aggregation, adherence and vector competence greatly alter elimination

Parameter symbol Definition Value Source
n Size of population in simulation 1000 unless otherwise stated N/A
λ Number of bites per mosquito 10 per month [37, 38]
V/H Ratio of number of vectors to hosts Fitted to data N/A
α max Age at which exposure to mosquitoes reaches its maximum level 20.0 [12]
ψ 1 Proportion of L3 leaving mosquito per bite 0.414 [39]
ψ 2 Proportion of L3 leaving mosquito that enter host 0.32 [40]
s 2 Proportion of L3 entering host that develop into adult worms 0.00275 [7, 41]
μ Death rate of adult worms 0.0104 per month [42]
α Production rate of Mf per worm 0.2 per month [39]
γ Death rate of Mf 0.1 per month [39, 43]
ɡ Proportion of mosquitoes which pick up infection when biting an infected host 0.37 [45]
σ Death rate of mosquitoes 5 per month [40]
k Aggregation parameter of individual exposure to mosquitoes Fitted to data [23, 24]
h(a) Parameter to adjust rate at which individuals of age α are bitten Linear from 0 to 10, with maximum of 1 [7]
χ 1 Proportion of Mf killed for an individual MDA round using ALB & DEC 0.95 [46, 47]
κ 1 Proportion of adult worm permanently sterlised during MDA round using ALB & DEC 0.55 [46, 47]
ρ Systematic adherence of MDA Varied N/A
p C Coverage of MDA Varied N/A
p N Coverage of LLIN Varied N/A
ρ BC Correlation between bite exposure and adherence to MDA Varied N/A
ρ CN Correlation between adherence to MDA & LLIN Varied N/A