Fig. 2

Impact of different treatment strategies on the prevalence of morbidity in (a) the overall community, (b) Pre-SAC & SAC and (c) adults. Two different transmission settings were explored; intermediate (R₀ = 2.5), and high (R₀ = 5) – as measured by the basic reproductive number (R₀) [11]. Panels a & d illustrate the overall mean number of worms across all ages, panels (b) & (e), the mean number of worms in children (Pre-SAC and SAC, 2–14 year olds), panels (c) & (f) the mean number of worms in adults (≥15 year olds). The different styled lines represent different treatment strategies: solid – annual targeted treatment (Pre-SAC and SAC), dashed – biannual targeted treatment (Pre-SAC and SAC), and dotted – annual community-wide treatment (Pre-SAC, SAC and adults). Individuals under two years of age were not eligible for treatment. The results assume 80 % coverage per round of targeted age group(s), and 94.8 % treatment efficacy. The results employ the lower intensity thresholds for morbidity (presented in Table 1). The corresponding results using the higher intensity threshold are presented in Additional file 1: Figure S2