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Table 5 Study 1: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

  Mean Control Afoxolaner Spinosad
Day 0 - 1 hour Geometric 81.0 (0.1) 90.6 (0.1) 85.1 (0.1)
  Arithmetic 82.7 (4.3) 90.8 (4.3) 85.2 (4.3)
Day 0 - 3 hours Geometric 81.8 (0.3) 76.7 (0.3) 18.4 (0.3)b,c
  Arithmetic 82.3 (6.1) 77.7 (6.1) 27.8 (6.1)b,c
Day 7 - 1 hour Geometric 95.3 (0.1) 83.7 (0.1) 70.8 (0.1)d
  Arithmetic 95.5 (4.2) 84.0 (4.7) 72.8 (4.7)d
Day 7 - 3 hours Geometric 88.8 (0.4) 49.1 (0.4) 5.4 (0.4)e,f
  Arithmetic 89.3 (6.6) 57.7 (6.6)g 8.5 (6.6)e,f
  1. aCounts of live fleas with normal movement; excludes those with abnormal movement, classified as moribund
  2. Treated group different from control: b p ≤ 0.0045; d p ≤ 0.0133;e p ≤ 0.0001; g p = 0.0039
  3. Different from afoxolaner: c p ≤ 0.0001; f p ≤ 0.0054