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Table 5 Study 1: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

 

Mean

Control

Afoxolaner

Spinosad

Day 0 - 1 hour

Geometric

81.0 (0.1)

90.6 (0.1)

85.1 (0.1)

 

Arithmetic

82.7 (4.3)

90.8 (4.3)

85.2 (4.3)

Day 0 - 3 hours

Geometric

81.8 (0.3)

76.7 (0.3)

18.4 (0.3)b,c

 

Arithmetic

82.3 (6.1)

77.7 (6.1)

27.8 (6.1)b,c

Day 7 - 1 hour

Geometric

95.3 (0.1)

83.7 (0.1)

70.8 (0.1)d

 

Arithmetic

95.5 (4.2)

84.0 (4.7)

72.8 (4.7)d

Day 7 - 3 hours

Geometric

88.8 (0.4)

49.1 (0.4)

5.4 (0.4)e,f

 

Arithmetic

89.3 (6.6)

57.7 (6.6)g

8.5 (6.6)e,f

  1. aCounts of live fleas with normal movement; excludes those with abnormal movement, classified as moribund
  2. Treated group different from control: b p ≤ 0.0045; d p ≤ 0.0133;e p ≤ 0.0001; g p = 0.0039
  3. Different from afoxolaner: c p ≤ 0.0001; f p ≤ 0.0054