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Table 6 Study 2: mean (standard error) (SE) live flea countsa of control, afoxolaner and spinosad group dogs

From: Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies

  Mean Control Afoxolaner Spinosad
Day 0 - 1 hour Geometric 81.2 (0.1) 86.0 (0.1) 71.0 (0.1)
  Arithmetic 81.8 (4.2) 86.3 (4.2) 71.8 (4.2)b
Day 0 - 3 hours Geometric 89.8 (0.3) 33.9 (0.3)c 0.0 (0.0)d,e
  Arithmetic 90.0 (9.6) 51.2 (9.6)c 0.0 (0.0)d,e
Day 7 - 1 hour Geometric 89.9 (0.4) 88.9 (0.4) 4.0 (0.4)d,e
  Arithmetic 90.3 (3.9) 89.2 (3.9) 9.5 (3.9)d,e
Day 7 - 3 hours Geometric 89.8 (0.1) 54.3 (0.1)f 0.0 (0.6)d,e
  Arithmetic 89.8 (0.1) 56.7 (4.1)f 0.0 (0.0)d,e
  1. aCounts of live fleas with normal movement; excludes those with abnormal movement, classified as moribund
  2. Treated group different from control: c p ≤ 0.0220; d p < 0.0001; f p ≤ 0.0006
  3. Different from afoxolaner: b p = 0.0276; e p < 0.0001