Table 4 Number of predicted house dust mite allergen homologs identified in the Sarcoptes scabiei genome
Allergen group | Biochemical function | No. of homologs |
|---|---|---|
1 | Cysteine protease | >10 |
2 | Lipid binding protein | 1 |
3 | Serine protease | >18 |
4 | α-Amylase | 0 |
5 | Structural protein | 0 |
6 & 9 | Serine protease | 1 |
7 | Lipopeptide binding protein | 2 |
8 | Glutathione-S-transferase | 5 |
10 | Tropomyosin | 2 |
11 | Paramyosin | 1 |
12 | Possible chitinase | 0 |
13 | Fatty acid binding protein | 1 |
14 | Apolipophorin | 1 |
15 | Chitinase | 1 |
16 | Gelsolin | 1 |
17 | Calcium-binding EF-hand protein | 5 |
18 | Chitinase | 1 |
19 | Antimicrobial peptide | 0 |
20 | Arginine kinase | 2 |
21 | Structural protein | 0 |
22 | Lipid binding protein | 1 |
23 | Chitin binding protein | 1 |
24 | Ubiquinol-cytochrome c reductase binding protein | 1 |
25 | Triose phosphate isomerase | 1 |
26 | Myosin, light chain | 11 |
27 | Serpin | 10 |
28 | Heat shock protein | 8 |
29 | Cyclophilin | 12 |
30 | Ferritin | 3 |
31 | Cofilin | 1 |
32 | Inorganic pyrophosphatase | 1 |
33 | α-Tubulin | 2 |