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Fig. 3 | Parasites & Vectors

Fig. 3

From: Effects of albendazole combined with TSII-A (a Chinese herb compound) on optic neuritis caused by Angiostrongylus cantonensis in BALB/c mice

Fig. 3

TSII-A promotes RGC survival of mice infected with A. cantonensis. a-f: Immunofluorescence reinforced the image of RGC cells labeled with Brn-3A (Green). Scale bar = 100 μm. a Normal control. b: Untreated mice infected with A. cantonensis (21 dpi). c: Albendazole (AB) for 7 days after 14 dpi with A. cantonensis. d: Albendazole combined with Dexamethasone (AB + De) for 7 days after 14 dpi with A. cantonensis. e: Albendazole combined with CPT (AB + CPT) for 7 days after 14 dpi with A. cantonensis. f: Albendazole combined with TSII-A (AB + TSII-A) for 7 days after 14 dpi with A. cantonensis. g: Data are mean ± SEM of ganglion cell numbers in normal group, untreated group for 21 dpi with A. cantonensis, and treated group for 7 days after 14 dpi with A. cantonensis infection, respectively. *Statistically significant when compared with control (0 dpi); # statistically significant when compared with 21 dpi; statistically significant when compared with albendazole treatment group, ▲ statistically significant when compared with Albendazole combined with Dexamethasone treatment group; N = 3 coverslips per group, with 5fields analyzed per coverslip, P < 0.05

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