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Table 2 IC50 values generated by resazurin, CellTiter-Glo® and Vybrant® compared to microscopic values

From: Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays

  Resazurin CellTiter-Glo® Vybrant®
Drug IC50 SpectraMax (μM) IC50 Microscopic Readout (μM) IC50 SpectraMax (μM) IC50 Microscopic Readout (μM) IC50 SpectraMax (μM) IC50 Microscopic Readout (μM)
Praziquantel not calculable 1.7 ± 1.5 not calculable 1.3 ± 0.9 not calculable 2.4 ± 1.2
Mefloquine not calculable 2.6 ± 1.1 4.9 ± 2.9 2.4 ± 1.3 7.9 ± 1.7 1.7 ± 0.3
Oxamniquine not calculable 135.1 ± 128.8 194.5 ± 52.6 87.7 ± 49.7 not calculable 20.3 ± 9.5