HisAK70: progress towards a vaccine against different forms of leishmaniosis

Parasites & Vectors

Table 1 The arginine metabolism and cytokine production in mice infected with L. infantum at 42 days after infection

Groups of mice	μM	mU	Ratio	pg/ml
Groups of mice	Nitrites	Arginase activity	IFN-γ/IL-10	IL-13
PBS	8 ± 3	32 ± 5	3,0	218 ± 46
Empty vector	9 ± 4	23 ± 2	2,6	234 ± 38
HisAK70	21 ± 3 (*)	8 ± 3 (*)	7,5 (*)	396 ± 50 (*)

Data are presented as the mean ± S.D. (n = 5). Asterisks indicate P < 0.05 with respect to control mice

ISSN: 1756-3305