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Table 3 Susceptibility of promastigotes of L. infantum to oxidative and nitrosative stress

From: Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection

L. infantum strain

IC50 (μM)

H2O2

Menadione

NONOate

ITMAP-263

43 ± 11

2.6 ± 0.4

>4000

IMT-151

92 ± 15

3.9 ± 0.2 (*)

2190 ± 360 (*)

IMT-202

71 ± 29

4.7 ± 0.2 (*)

1560 ± 530 (*)

  1. (*) p < 0.05, versus ITMAP-263)
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Parasites & Vectors

ISSN: 1756-3305

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