Diversity and evolutionary genetics of the three major Plasmodium vivax merozoite genes participating in reticulocyte invasion in southern Mexico

Table 2 Natural selection and recombination of P. vivax genes encoding merozoite proteins

Merozoite gene fragment	Geographic origin	N	dN-dS				Recombination Rm
Merozoite gene fragment	Geographic origin	N	*Synonymous	*Non-synonymous	Z-test	p	Recombination Rm
*msp1* ₄₂	SMX	35	6	34	1.276	0.102	9
	Global	632	21	88	2.755	0.007	22
*ama1* _I-II	SMX	35	1	13	2.157	0.016	3
	Global	607	15	36	1.562	0.121	17
*dbp* _II	SMX	35	0	10	3.161	0.001	1
	Global	896	34	125	2.587	0.005	18

SMX, southern Mexico; N, number of sequences; Rm, minimal number of recombination events. msp1 ₄₂, 981pb; ama1 _I-II, 780pb; dbp _II, 663pb. *Codons with multiple evolutionary paths were excluded from the analysis

ISSN: 1756-3305