Scheme 3From: Oxadiazole-2-oxides may have other functional targets, in addition to SjTGR, through which they cause mortality in Schistosoma japonicum Synthesis of compounds 22–30. Reagents and conditions: (b) NBS, AIBN, CCl4, 80 °C, overnight, 54 %; (c) aromatic alcohols, or Cs2CO3, DMF, 30–60 °C, 25–45 %Back to article page