Table 2 Treatment effects of oxadiazole-2-oxides on juvenile S. japonicum in mice

Control

7

10.8 ± 0.8

8,032.9 ± 2,192.1

Compound 4a

4

1.3 ± 0.8 (P > 0.05^**)

87.7 (P < 0.01^*)

4,258.9 ± 1,910.0 (P > 0.05^**)

47.0 (P < 0.05^*)

Compound 4b

2

1.8 ± 1.5 (P > 0.05^**)

83.1 (P < 0.01^*)

8,669.2 ± 2,255.8 (P < 0.05^**)

–

Compound 7c

2

1.4 ± 0.8 (P > 0.05^**)

87.1 (P < 0.01^*)

3,859.4 ± 3,749.4 (P > 0.05^**)

52.0 ( P > 0.05^*)

Compound 13

2

1.7 ± 0.7 (P > 0.05^**)

84.6 (P < 0.01^*)

3,808.9 ± 1,288.9 (P > 0.05^**)

52.6 (P < 0.05^*)

Compound 16

5

1.0 ± 0.5 (P > 0.05^**)

90.8 (P < 0.01^*)

4,054.5 ± 1,322.1 (P > 0.05^**)

49.5 (P < 0.01^*)

Compound 20

6

3.0 ± 0.9 (P < 0.05^**)

69.5 (P < 0.01^*)

7,767.5 ± 2,676.6 (P < 0.05^**)

3.3 (P > 0.05^*)

AS

4

2.3 ± 1.0

78.5 (P < 0.01^*)

2,932.2 ± 1,149.3

63.5 (P < 0.01^*)