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Table 5 The effect of covariates on average egg reduction rates among children infected with schistosomes following treatment with praziquantel

From: New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel

Covariates Levels ERR (95 % CI)
Schistosoma haematobium dataset
(Baseline) Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up 99.7 % (97.4 %, 100 %)
Country Kenyaa 99.8 % (98.8 %, 100 %)
Sex Female 99.7 % (95.7 %, 100 %)
Age group Older SAC 95.9 % (85.8 %, 98.8 %)
Schistosoma mansoni dataset
(Baseline) Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up 95.4 % (83.1 %, 98.8 %)
Country Uganda 85.3 % (73.5 %, 91.8 %)
Dose 60 mg/kg 98.5 % (90.8 %, 99.8 %)
Sex Female 93.2 % (74.1 %, 98.2 %)
Age group Pre-SAC 95.3 % (80.9 %, 98.8 %)
  Older SAC 96.6 % (85.8 %, 99.2 %)
Follow-up time 28 days 84.9 % (76.7 %, 90.1 %)
  42 days 73.6 % (53.2 %, 85.1 %)
  1. Abbreviations: CI confidence intervals, SAC school-age children
  2. aChildren in Kenya were followed up for 42 days