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Table 6 The effect of covariates on the percentage of egg reduction rates greater than 90 % among children infected with schistosomes following treatment with praziquantel

From: New approaches to measuring anthelminthic drug efficacy: parasitological responses of childhood schistosome infections to treatment with praziquantel

Covariates

Levels

Percentage ERR > 90 % (95 % BCI)

Schistosoma haematobium dataset

(Baseline)

Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up

95.9 % (89.3 %, 99.1 %)

Country

Kenyaa

98.3 % (94.3 %, 99.7 %)

Sex

Female

97.3 % (92.2 %, 99.4 %)

Age group

Older SAC

92.3 % (82.6 %, 97.6 %)

Schistosoma mansoni dataset

(Baseline)

Côte d’Ivoire; male; younger SAC; 40 mg/kg; 21 days follow-up

94.4 % (85.3 %, 98.3 %)

Country

Uganda

75.9 % (59.7 %, 86.4 %)

Dose

60 mg/kg

92.3 % (77.8 %, 98.1 %)

Sex

Female

92.6 % (81.8 %, 97.6 %)

Age group

Pre-SAC

90.9 % (78.1 %, 97.2 %)

 

Older SAC

95.5 % (85.8 %, 99.0 %)

Follow-up time

28 days

89.5 % (80.4 %, 95.0 %)

 

42 days

59.1 % (39.7 %, 76.4 %)

  1. aChildren in Kenya were followed up for 42 days
  2. Abbreviations: BCI Bayesian credible interval, SAC school-age children