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Table 1 Pairwise comparisons of sequence identity (%) of proteins representing the insulin/insulin-like growth factor 1(IGF1)-like signalling pathway (IIS) between Haemonchus contortus and Caenorhabditis elegans

From: Reconstruction of the insulin-like signalling pathway of Haemonchus contortus

Protein Scaffold Transcripts representing the IIS genes Length (aa) Homologs in C. elegans (Gene code) Length (aa) Pairwise sequence identity (%)
Hc-INS-1a scaffold1633 Locus_6343_Transcript_1/2_Confidence_0.667_Length_624 100 F13B12.5 109 42.0
Hc-INS-1b scaffold11919 Locus_3137_Transcript_1/2_Confidence_0.750_Length_686 100 F13B12.5 109 42.0
Hc-INS-17 - Locus_4104_Transcript_1/1_Confidence_1.000_Length_511 106 F56F3.6 108 54.7
Hc-INS-18 - Locus_1267_Transcript_2/3_Confidence_0.600_Length_720 70 T28B8.2 95 47.4
Hc-DAF-2 scaffold13413 Locus_7014_Transcript_2/3_Confidence_0.714_Length_5695 1455 Y55D5A.5a, b, c*, d, e, f, g 672–1928 25.5–34.6
Hc-IST-1 scaffold434 Locus_5794_Transcript_4/8_Confidence_0.650_Length_4263 + Locus_5794_Transcript_6/8_Confidence_0.500_Length_3032 1441 C54D1.3 1003 18.4
Hc-AAP-1 scaffold6618 Locus_7479_Transcript_1/1_Confidence_1.000_Length_1541 427 Y110A7A.10 522 36.1
Hc-AGE-1a C279481 Locus_4139_Transcript_1/1_Confidence_1.000_Length_3713 1156 B0334.8a 1182 40.5
Hc-AGE-1b scaffold1062 Locus_10568_Transcript_2/2_Confidence_0.800_Length_3699 1149 B0334.8a 1182 40.6
Hc-DAF-18   Locus_6617_Transcript_3/3_Confidence_0.714_Length_3487 800 T07A9.6 962 24.0
Hc-PDK-1 C457723 Locus_2599_Transcript_2/3_Confidence_0.500_Length_2764 576 H42K12.1a, b* 632–636 41.8–42.4
Hc-SGK-1a - Locus_1010_Transcript_1/1_Confidence_1.000_Length_1434 462 W10G6.2a*, b 453–463 60.0–61.2
Hc-SGK-1b - Locus_5956_Transcript_1/1_Confidence_1.000_Length_1384 428 W10G6.2a*, b* 453–463 63.1
Hc-AKT-1a scaffold15637 Locus_6593_Transcript_2/2_Confidence_0.857_Length_2281 540 C12D8.10a*, b, c 254–546 73.2–75.9
Hc-AKT-1b scaffold17120 Locus_44_Transcript_10/11_Confidence_0.651_Length_6534 552 C12D8.10a, b*, c 254–546 73.2–77.6
Hc-PPTR-1a scaffold4564 Locus_1388_Transcript_2/4_Confidence_0.700_Length_4420 542 W08G11 542 80.1
Hc-PPTR-1b C217263 Locus_3418_Transcript_2/2_Confidence_0.667_Length_3679 542 W08G11 542 80.1
Hc-PPTR-1c C426137 Locus_351_Transcript_5/7_Confidence_0.556_Length_5020 542 W08G11 542 80.1
Hc-PPTR-2 scaffold6183 Locus_8402_Transcript_1/1_Confidence_1.000_Length_3588 476 C13G3.3a*, b, c*, d* 557–607 70.1–71.2
Hc-FTT-2 - Locus_4342_Transcript_1/6_Confidence_0.556_Length_1420 206 F52D10.3a, b* 198–248 80.5–84.3
Hc-PAR-5 - Locus_4342_Transcript_5/6_Confidence_0.667_Length_1898 + Locus_4342_Transcript_3/6_Confidence_0.667_Length_1669 201 M117.2a*, b 126–248 48.4–82.6
Hc-DAF-16 C472265 Locus_5600_Transcript_3/3_Confidence_0.714_Length_3611 589 R13H8.1a, b, c, d, e, f, g, h, i, k, l, m* 303–589 32.4–43.2
Hc-SKN-1 scaffold10742 Locus_3183_Transcript_5/6_Confidence_0.684_Length_3607 612 T19E7.2a, b, c, d* 223–623 30.3–38.5
Hc-HSF-1a scaffold1518 Locus_7749_Transcript_2/2_Confidence_0.875_Length_2372 544 Y53C10A.12 671 33.5
Hc-HSF-1b scaffold3772 Locus_497_Transcript_5/5_Confidence_0.577_Length_2356 544 Y53C10A.12 671 33.5
Hc-HSB-1 scaffold9500 Locus_3235_Transcript_1/1_Confidence_1.000_Length_453 91 K08E7.2 80 60.0
Hc-DDL-1 scaffold11860 Locus_4675_Transcript_1/2_Confidence_0.750_Length_767 + Locus_8707_Transcript_2/3_Confidence_0.667_Length_738 129 F59E12.10 189 27.1
Hc-EGL-9a scaffold12571 Locus_5190_Transcript_1/1_Confidence_1.000_Length_1701 504 F22E12.4a, b, c, d*, e 363–723 14.9–48.6
Hc-EGL-9b C449377 Locus_3254_Transcript_2/2_Confidence_0.333_Length_2254 482 F22E12.4a, b, c, d*, e 363–723 14.9–51.2
Hc-EGL-9c scaffold12558 Locus_1766_Transcript_1/1_Confidence_1.000_Length_2016 482 F22E12.4a, b, c*, d, e 363–723 14.9–49.5
Hc-EGL-9d C457287 Locus_4349_Transcript_1/1_Confidence_1.000_Length_1791 482 F22E12.4a, b, c*, d, e 363–723 14.9–49.5
  1. C. elegans isoforms with the highest pairwise sequence identity to H. contortus homologs are marked (*)