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Table 1 Study 1: Knock-down effect at 1 h and arithmetic mean flea counts and preventive efficacies at 1 h and 12 h (speed of kill) of the combination of permethrin and fipronil (group 2) and fipronil alone (group 3) based on arithmetic counts

From: Knock-down and speed of kill of a combination of fipronil and permethrin for the prevention of Ctenocephalides felis flea infestation in dogs

  Knock-down effect (%) at 1 h Mean flea counts and preventive efficacy (%)
at 1 h at 12 h
Group 2 Group 3 Group 1 Group 2 Group 3 Group 1 Group 2 Group 3
Fipronil/permethrin Fipronil Control Fipronil/permethrin Fipronil Control Fipronil/permethrin Fipronil
D7 65.2 %a 7.8 % 85.5 1.2a (98.6 %) 51.2 (40.2 %) 60.7 0.0 (100.0 %) 0.9 (99.0 %)
D14 67.7 %a 5.8 % 80.7 2.5a (96.9 %) 45.7 (43.4 %) 61.5 0.0 (100.0 %) 0.0 (100.0 %)
D21 68.5 %a 4.2 % 76.5 5.3a (93.0 %) 55.7 (27.2 %) 52.7 0.0 (100.0 %) 0.0 (100.0 %)
D28 58.2 %a 2.0 % 53.2 14.2a (73.4 %) 62.0 (0.0 %) 47.2 0.3 (99.3 %) 0.2 (99.6 %)
  1. a statistically significant increased efficacy in the fipronil + permethrin group compared to the fipronil alone group (p < 0.05)