Treatment | Day of infestation | ||||||||
---|---|---|---|---|---|---|---|---|---|
0 | 14 | 28 | 44 | 58 | 74 | 90 | 95 | ||
Placebo | Range | 11 to 35 | 17 to 37 | 20 to 39 | 24 to 37 | 13 to 26 | 12 to 34 | 20 to 26 | 20 to 38 |
AM | 20.8 | 24.1 | 31.6 | 28.3 | 21.4 | 26.8 | 22.3 | 29.1 | |
GMd | 19.7a | 23.5a | 31.1a | 28.0a | 20.8a | 25.8a | 22.2a | 28.7a | |
Sarolaner | Range | 0 to 11 | 2 to 12 | 7 to 14 | 5 to 14 | 9 to 23 | 12 to 38 | 5 to 22 | 20 to 33 |
AM | 1.6 | 8.0 | 10.0 | 10.0 | 17.0 | 26.9 | 12.1 | 25.5 | |
AM Efficacy (%) | 92.2 | 66.8 | 68.4 | 64.6 | 20.5 | 0.0 | 45.5 | 12.4 | |
GMd | 0.6b | 7.3b | 9.7b | 9.6b | 16.3a | 25.7a | 11.1b | 25.1a | |
GM Efficacy (%) | 96.8 | 69.0 | 68.7 | 65.7 | 21.6 | 0.3 | 49.8 | 12.4 | |
P-value vs. placebo | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.2065 | 0.9863 | 0.0005 | 0.4861 | |
Fluralaner | Range | 0 to 2 | 2 to 11 | 3 to 10 | 5 to 19 | 9 to 24 | 19 to 32 | 5 to 17 | 21 to 29 |
AM | 0.4 | 5.9 | 5.8 | 11.0 | 16.4 | 24.4 | 12.8 | 24.9 | |
AM Efficacy (%) | 98.2 | 75.6 | 81.8 | 61.1 | 23.4 | 8.9 | 42.7 | 14.6 | |
GMd | 0.3b | 5.3b | 5.3c | 9.9b | 15.4a | 23.9a | 12.1b | 24.7a | |
GM Efficacy (%) | 98.7 | 77.5 | 83.1 | 64.5 | 26.1 | 7.3 | 45.4 | 13.7 | |
P-value vs. placebo | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.1267 | 0.6959 | 0.0027 | 0.4485 | |
P-value vs. sarolaner | 0.2720 | 0.2450 | 0.0238 | 0.8946 | 0.8149 | 0.7673 | 0.7431 | 0.9509 |