Unique PFK regulatory property from some mosquito vectors of disease, and from Drosophila melanogaster

Parasites & Vectors

Table 1 Kinetic parameters of Aedes aegypti PFK upon addition of its substrates F6P and ATP

PFK activity was measured at pH = 7.4, F6P and ATP range 0.1–8.0 mM. Kinetic parameters for the substrate curves were calculated by non-linear regression using the software Sigma-Plot 10 (Systat, CA, USA). Values are the mean ± SEM. Data from three independent experiments were used to fit through the equations described in the Methods. Vmax - maximal velocity; h – Hill’s coeficient; Kprime – K_0.5^h, Ki – constant of inhibition

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