Investigating associations between biting time in the malaria vector Anopheles arabiensis Patton and single nucleotide polymorphisms in circadian clock genes: support for sub-structure among An. arabiensis in the Kilombero valley of Tanzania

Table 3 Tajima’s D statistics including synonymous and non-synonymous mutations and nucleotide diversity in 8 clock genes and among early and late feeding phenotypes of An. arabiensis

Chr^a	Gene ID^b	Gene^c	Pop^d	N^e	n_s ^f	∏(%)^g	D^h	μ_s ⁱ	μ_NS ^j	μ_NCS ^k	SNPd^l	LE:LL^m	SE:SLⁿ	LE:SE^o	LL:SL^p	Cod^q pos
2L	AGAP005711	Clk E018627	LE	30	12	0.0057	−1.6620	7	4	7	24.31	6	4	7	4	1
			LL	26	7	0.0034	−1.2588	7	0	7
			SE	30	8	0.0032	−1.5161	8	0	8
			SL	24	4	0.0032	−0.1632	4	0	4
2R	AGAP001958	Cry1 E041560	LE	22	8	0.0051	−0.9904	1	7	1	27.36	7	6	7	6	2
			LL	18	10	0.0050	−1.7391	1	9	1
			SE	28	10	0.0061	−0.9119	1	9	1
			SL	20	6	0.0054	−0.1223	1	5	1
2R	AGAP004261	Cry2 E051011	LE	28	16	0.0057	−0.5965	0	16	NA 0	31.31	12	13	15	13	1
			LL	20	15	0.0054	−0.9156	0	15	0
			SE	36	16	0.0050	−0.7496	0	16	0
			SL	22	15	0.0054	−0.7795	0	15	0
2L	AGAP005655	Cyc E018454In5	LE	18	16	0.0138	−0.1541	5	10	5	9.53	13	25	16	23	1
			LL	18	32	0.0301	−0.8217	7	21	7
			SE	20	26	0.0277	0.5346	6	16	6
			SL	16	23	0.0198	−0.7512	6	16	6
2L	AGAP006376	Pdp1 E021381	LE	28	3	0.0021	−1.3214	3	0	3	56.33	0	0	0	0	1
			LL	20	0	NA	NA	NA	NA	NA
			SE	26	0	NA	NA	NA	NA	NA
			SL	26	2	0.0009	−1.5131	2	0	2
3R	AGAP001856	Per PAS	LE	26	5	0.0033	0.0343	0	5	0	68	4	3	4	4	1
			LL	18	5	0.0037	0.1080	0	5	0
			SE	26	4	0.0036	0.1083	0	4	0
			SL	20	4	0.0028	0.0781	0	4	0
3R	AGAP001856	Tim E052569	LE	42	17	0.0073	0.4200	15	2	15	31.82	12	11	11	11	1
			LL	32	12	0.0076	1.1916	10	2	10
			SE	20	11	0.0057	1.6610	10	1	10
			SL	22	14	0.0071	0.3339	13	1	13
3R	AGAP007801	Vri E027461b	LE	28	4	0.0018	−0.4212	0	4	0	125.75	2	3	2	1	3
			LL	18	2	0.0010	0.9062	0	2	0
			SE	30	3	0.0014	0.2328	0	3	0
			SL	18	3	0.0014	−0.2589	0	3	0

^aChromosome, ^b An. gambiae reference gene ID, ^cGene, ^eNumber of haplotype sequences, ^fNumber of segregating sites, ^gNucleotide diversity, ^hTajima’s D, ⁱNumber of synonymous mutations, ^jNumber of non-synonymous mutations, ^kNumber of silent mutations, ^lSNP density i.e. number of SNPs found in a given number of nucleotide base-pairs, ^mshared polymorphisms between early and late in Sagamaganga, ⁿshared polymorphisms between early and late in Sagamaganga, ^oshared polymorphisms in early biting between Lupiro and Sagamaganga, ^pshared polymorphisms in late biting between Lupiro and Sagamaganga, and ^qCodon at which the SNP occurs

ISSN: 1756-3305