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Table 3 Ion channels of parasitic flatworms described in the published literature and whether they were identified and classified correctly using our bioinformatic pipeline (MuSICC)

From: Pipeline for the identification and classification of ion channels in parasitic flatworms

Name

Protein ID

Species

Identified/characterised*

Classified

Key references

Shaker-related K+ channel

SKv1.1

Schistosoma mansoni

1/1

1

[72]

P2X receptor

SchP2X

Schistosoma mansoni

3/3

3

[73]

Nicotinic acetylcholine receptors

ShAR2beta

Schistosoma haematobium

2/1

2

[60]

Ca2+ channel beta subunits

-

Schistosoma mansoni

1/1

1

[74, 75]

Novel glutamate-gated chloride channel subunits

SmGluCl

Schistosoma mansoni

4/4

0

[61]

Acetylcholine-gated chloride channels

SmACCs

Schistosoma mansoni

3/2

0

[19]

ATP-sensitive potassium channel

CsKir6.2

Clonorchis sinensis

0/1

0

[76]

Aquaporins

OvAQP

Opisthorchis viverrini

2/1

2

[77, 78]

  1. * Number of ion channels submitted to Swissprot (http://www.uniprot.org/) that are associated with the key references