Skip to main content
Fig. 6 | Parasites & Vectors

Fig. 6

From: Characterization of a Plasmodium berghei sexual stage antigen PbPH as a new candidate for malaria transmission-blocking vaccine

Fig. 6

Transmission-blocking activity of PbPH. a Effect of anti-PbPH sera on exflagellation of male gametocytes. Exflagellation centers per field were measured after 15 min incubation with anti-PbPH mice sera or control sera at final dilutions of 1:5, 1:10 and 1:50. Means were calculated from three separate experiments. Error bars indicate mean ± SEM (n = 3). **P < 0.01 (Student’s t test). b The effect of anti-PbPH sera at 1:5, 1:10, and 1:50 dilutions on P. berghei ookinete conversion in vitro. Means were calculated from three separate experiments. Error bars indicate mean ± SEM (n = 3). *P < 0.05; **P < 0.01 (Student’s t test). c Direct mosquito feeding assay on control mice and mice immunized with recombinant PbPH protein (5 mice per group). Mice were subsequently infected with wild-type P. berghei and used to assess TB activities. The data are representative of three independent experiments. Data points represent midgut oocyst numbers of individual mosquitoes in each group. Mean number of oocysts per midgut and the SEM are shown

Back to article page