Skip to main content

Table 1 Mosquito infection prevalence and oocyst intensity after feeding on control mice and mice immunized with recombinant PbPH

From: Characterization of a Plasmodium berghei sexual stage antigen PbPH as a new candidate for malaria transmission-blocking vaccine

  Control mice a PbPH-immunized mice a
M1 M2 M3 M4 M5 M1 M2 M3 M4 M5
Mosquitoes Infected/Dissected 28/25 28/27 29/27 30/29 29/27 30/24 32/27 31/25 30/24 32/25
Prevalence of infection (%) b 89.3 96.4 93.1 96.7 93.1 80 84.4 80.6 80 78.1
Mean prevalence (%)      93.72      80.62
Reduction in prevalence (%)c           13.1
Oocyst intensity d 96.5 98.70 106.80 106.60 93.97 54.10 49.53 46.65 58.39 52.94
SEM e 16.04 13.68 16.08 16.08 16.78 9.20 7.66 7.74 9.54 9.68
Mean oocyst intensity      100.51      52.32
Reduction in oocyst intensity f           47.95
  1. a Five mice were used in each group for the evaluation of TB activity
  2. b The prevalence of infection was calculated as the number of mosquitoes with oocysts/total mosquitoes dissected in each group × 100%
  3. c The percent reduction of prevalence was calculated as % mean prevalence control – % mean prevalence PbPH
  4. d Mean number of oocysts per mosquito midgut
  5. e Standard error of the mean
  6. f The percent reduction in oocyst intensity was calculated as (mean oocyst intensitycontrol – mean oocyst intensityPbPH)/mean oocyst intensity control × 100%