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Table 1 Identification of differentially expressed proteins

From: Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni

Spota

Identificationb

Proteinc

Species (GI)d

Hoste

Fold Changef

MW Exp/Theo

pI Exp/Theo

Genome

Transcriptome

Antioxidant and detoxifying enzymes

6

 

Dihydrolipoamide dehydrogenase

Schistosoma japonicum (226486712)

M

5.3

47.8/53.0

7.2/6.5

10

Aldo-keto reductase

S. mansoni (256080704)

R

2.9

33.6/33.5

6.4/7.7

12

Aldo-keto reductase

S. mansoni (256080704)

R

4.6

33.0/33.5

6.6/7.7

13

Aldo-keto reductase

S. mansoni (350645579)

M

2.0

31.3/35.5

6.7/7.7

16

Hydroxyacylglutathione hydrolase

Clonorchis sinensis (358335388)

M

1.8

25.0/29.6

6.9/6.9

17

Thiopurine S-methyltransferase

S. japonicum (226484786)

M

2.1

23.0/28.1

6.7/7.1

19

Glutathione S-transferase class-mu

Fasciola hepatica (3913799)

M

1.8

16.5/25.3

7.1/5.9

Metabolic enzymes

2

Leucine aminopeptidase

C. sinensis (156600435)

M

1.5

61.5/59.9

7.8/6.1

3

Retinal dehydrogenase 1

C. sinensis (358342257)

M

3.5

50.0/52.6

6.8/6.0

4

Hexokinase

C. sinensis (358342257)

M

1.9

48.7/50.0

7.2/6.2

5

6-phosphogluconate dehydrogenase

S. haematobium (844860554)

M

2.2

48.7/52.8

7.3/6.2

7

 

Malate dehydrogenase

C. sinensis (358332642)

M

5.1

47.8/55.7

7.3/6.6

8

Enolase

Echinostoma caproni (112950027)

M

1.7

45.5/46.1

6.8/6.4

Structural/Motor proteins

9

Putative actin

S. mansoni (353233111)

R

2.0

43.7/41.7

5.9/5.3

18

Regulator of microtubule dynamics protein 1

S. haematobium (844834702)

M

1.9

21.0/24.3

6.0/8.6

Cysteine proteases

15

Cathepsin L

F. gigantica (7271891)

R

2.3

26.1/37.0

6.1/5.5

Protein binding

11

Stress-induced phosphoprotein 1

C. sinensis (350002666)

M

2.8

32.4/36.3

6.5/6.3

Unknown

1g

Periostin

C. sinensis (358341487)

R

2.9

90.0/105.3

6.8/5.8

Fasciclin 1-like

Paragonimus westermani (119712173)

Gynecophoral canal protein

S. mansoni (1354127)

14

Putative TyrA protein

S. japonicum (226479962)

M

2.8

32.4/41.6

6.5/7.0

  1. Protein identification was performed using X!Tandem and MS-GF+ search engines on the Echinostoma caproni genome and transcriptome databases and BLASTp against NCBInr protein database. Spot numbers refer to gel image in Fig. 2
  2. aSpot reference number
  3. bPositive identification (√) in each of the two databases employed
  4. cIdentification details are compiled in Additional file 3
  5. dGI accession number in the Protein database of NCBI
  6. eHost species in which every protein spot was overexpress. (M) Mouse; (R) Rat
  7. fAverage Normalized Volume ratio
  8. gThree different proteins were associated with the same accession number both in the E. caproni genome and transcriptome databases