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Table 2 Toxicity of DOP2 antagonists to larvae of An. gambiae showing lethal concentration (LC50) values (μM ± SEM) (n ≥ 3)

From: Comparative pharmacological characterization of D1-like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatus suggests pleiotropic signaling in mosquito vector lineages

 

24 h

48 h

72 h

Amitriptyline

N.A. a

163 ± 22

151 ± 28

Amperozide

N.A. a

245 ± 68

182 ± 24

Asenapine

N.A. a

69 ± 15

28 ± 5

Chlorprothixene

163 ± 17

128 ± 84

112 ± 72

Methiothepin

137 ± 110

51 ± 30

N.A. b

  1. Mortality too low (a) or high (b) to accurately calculate LC50