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Table 2 Toxicity of DOP2 antagonists to larvae of An. gambiae showing lethal concentration (LC50) values (μM ± SEM) (n ≥ 3)

From: Comparative pharmacological characterization of D1-like dopamine receptors from Anopheles gambiae, Aedes aegypti and Culex quinquefasciatus suggests pleiotropic signaling in mosquito vector lineages

  24 h 48 h 72 h
Amitriptyline N.A. a 163 ± 22 151 ± 28
Amperozide N.A. a 245 ± 68 182 ± 24
Asenapine N.A. a 69 ± 15 28 ± 5
Chlorprothixene 163 ± 17 128 ± 84 112 ± 72
Methiothepin 137 ± 110 51 ± 30 N.A. b
  1. Mortality too low (a) or high (b) to accurately calculate LC50