Parameters (units)

Reference intervals^{g}

Day 0

Day 30

Day 180

Day 365


UPC ratio^{a}

< 0.5

0.3 ± 0.7

0.2 ± 0.2

0.2 ± 0.5

0.1 ± 0.3

Total protein (g/dl)^{b}

5.4–7.1

8.00 ± 3.05

7.08 ± 1.60

6.63 ± 0.67

6.70 ± 0.65

Albumin (g/dl)^{c}

2.6–3.3

2.66 ± 0.89

2.72 ± 0.65

3.33 ± 0.54

3.36 ± 0.53

Gammaglobulins (g/dl)^{d}

0.3–0.8

1.63 ± 3.03

0.91 ± 1.11

0.63 ± 0.28

0.61 ± 0.33

Hematocrit (%)^{e}

40–61

36 ± 13

39 ± 10

44 ± 7

46 ± 9

Hemoglobin (g/dl)^{f}

13.0–19.8

12.6 ± 4.2

13.7 ± 3.1

15.8 ± 2.6

16.3 + 4.0


^{a}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test, Z = 2.987 P = 0.003), day 180 (Z = 2.521 P = 0.012), day 365 (Z = 2.500 P = 0.012)]. Comparison between day 30  day 180 (Z = 0.456, P = 0.649), day 30  day 365 (Z = 0.533, P = 0.594) and day 180  day 365 (Z = 1.122, P = 0.262)

^{b}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test: Z = 3.676, P = 0.000237), day 180 (Z = 3.784, P = 0.000155) and day 365 (Z = 3.579, P = 0.000345)]. Comparison between day 30  day 180 (Z = 2.707, P = 0.007), day 30  day 365 (Z = 2.033, P = 0.042) and day 180  day 365 (Z = 0.205, P = 0.83)

^{c}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test: Z = 2.040, P = 0.041), day 180 (Z = 5.004, P < 0.0001) and day 365 (Z = 4.703, P < 0.0001)]. Comparison between day 30  day 180 (Z = 4.342, P < 0.0001), day 30  day 365 (Z = 3.530, P < 0.0001) and day 180  day 365 (Z = 0.573, P = 0.566)

^{d}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test: Z = 4116, P < 0.0001), day 180 (Z = 4.357, P < 0.0001) and day 365 (Z = 2.084, P = 0.037)]. Comparison between day 30  day 180 (Z = 3.752, P = 0.000175), day 30  day 365 (Z = 4.065, P < 0.0001) and day 180  day 365 (Z = 0.379, P = 0.705)

^{e}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test: Z = 2.655, P = 0.008), day 180 (Z = 4.379, P < 0.0001) and day 365 (Z = 3.977, P < 0.0001)]. Comparison between day 30  day 180 (Z = 2.657, P = 0.008), day 30  day 365 (Z = 3.322, P = 0.020) and day 180  day 365 (Z = 1.202, P = 0.229)

^{f}Comparison between day 0 and the other days [day 30 (Wilcoxon signedrank test: Z = 2.806, P = 0.005), day 180 (Z = 4.243, P < 0.0001) and day 365 (Z = 3.521, P = 0.000431)]. Comparison between day 30  day 180 (Z = 3.181, P = 0.001), day 30  day 365 (Z = 3.124, P = 0.002) and day 180  day 365 (Z = 1.384, P = 0.166)

^{g}UAB hematological and biochemical laboratory reference intervals