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Table 3 Demographic and clinical characteristics of dogs infected with Borrelia persica included in the study

From: Borrelia persica infection in dogs and cats: clinical manifestations, clinicopathological findings and genetic characterization

Dog number (sample ID) 1 (61887) 2 (8726) 3 (4663) 4 (9835) 5 (8692)
Location Yavne' el Meitar Hashmonaim Karmei Yosef Amatzia
Year of diagnosis 2003 2012 2012 2013 2015
Sex; age in years M; 1.5 F; 3 M; 4 F; 12.5 M; 2.5
Breed Siberian Husky Mixed breed Labrador Mixed breed German Shepherd
Fever 40.8 ° C 41.2 °C 39.5 °C –; (38.9 ° C) 39.4 °C
Lethargy + + + + +
Anorexia + + + + +
Pale mucous membranes + + + -
Icterus + -
Anemia + + + + -
Hematocrit L/L 0.271 0.340 0.189 0.270 0.375
MCV fL 75.3 77.7 66.7 69.2 67.5
MCHC g/l 305 305 337 353 381
Leukocytosis -
WBC number × 109/l 10.69 11.80 12.80 9.13 7.70
Thrombocytopenia + + +
PLT number × 109/l 168 41 171 86 39
Co-infection:      
PCR for E. canis -
PCR for Babesia sp. + + + -
Antibiotic treatment ciprofloxacin for 2 days and then doxycycline doxycycline long acting tetracycline and amoxicillin/clavulanic acid amoxicillin initially, continued with doxycycline doxycycline
Survival and response to treatment survived; no spirochetemia at recheck 7 days after treatment initiation survived; no spirochetemia at recheck 11 days after treatment initiation; treated also with imidocarb dipropionate for babesiosis died one day after treatment initiation survived; improved a day after initial treatment with amoxicillin; treated also with imidocarb dipropionate for babesiosis survived; recovered clinically at recheck 4 days after treatment initiation
  1. Hematocrit, reference range 0.371–0.57 L/L; MCV mean cell volume, range 58.8–71.2 fL; MCHC mean corpuscular hemoglobin concentration, range 310–362 g/l; WBC white blood cells, range 5.2–13.9 × 109/L; PLT: platelets, range 150–400 × 109/l