Table 1 Risk of mortality (hazard ratio) along with the 95 % CI, z and P-value for each treatment group relative to the control

NA500

0.43 (0.27–0.68)

3.6

0.0002

NA1000

0.52 (0.33–0.82)

2.8

0.005

NA2000

30.54 (13.13–71.05)

7.9

2.11e^-15

NA500

1.31 (0.4–4.3)

0.447

0.6

NA1000

2 (0.6–6)

1.139

0.2

NA2000

40 (11–140)

5.773

7.8e^-9

NA500

0.9 (0.57–1.4)

0.404

0.68

NA1000

2.17 (1.39–3.37)

3.418

0.0006

NA2000

1.24 (0.8–1.9)

0.969

0.33

NA50

0.08 (0.03–0.19)

5.5

3.17e^-08

NA100

0.04 (0.02–0.12)

6.5

8.13e^-11

NA200

0.05 (0.02-0.13)

6.4

1.82e^-10

NA12.5

1.2 (1.05–1.7)

1.1

0.06

NA25

0.93 (0.7–1.2)

0.5

0.56

NA50

0.25 (0.18–0.33)

9

< 2e^-16