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Table 2 Accuracy and precision of the detection of NATOG using UPLC-MS/MS (n = 8)

From: Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection

  QC-Low (2 μM) QC-Medium (10 μM) QC-High (50 μM)
Milli-Q Water    
 Mean 2.12 10.8 48.5
 Standard deviation 0.07 0.40 0.39
 Coefficient of variation (%) 3.5 3.7 0.8
 % Accuracy 106 108 96.9
Human urine    
 Mean 2.23 11.0 55.1
 Standard deviation 0.07 0.35 2.32
 Coefficient of variation (%) 3.3 3.2 4.2
 % Accuracya 112 110 110
  1. aEndogenous level of NATOG used for preparation of QC samples was 0.31 μM; results have not been corrected for the endogenous levels