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Table 2 Accuracy and precision of the detection of NATOG using UPLC-MS/MS (n = 8)

From: Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection

 

QC-Low (2 μM)

QC-Medium (10 μM)

QC-High (50 μM)

Milli-Q Water

   

 Mean

2.12

10.8

48.5

 Standard deviation

0.07

0.40

0.39

 Coefficient of variation (%)

3.5

3.7

0.8

 % Accuracy

106

108

96.9

Human urine

   

 Mean

2.23

11.0

55.1

 Standard deviation

0.07

0.35

2.32

 Coefficient of variation (%)

3.3

3.2

4.2

 % Accuracya

112

110

110

  1. aEndogenous level of NATOG used for preparation of QC samples was 0.31 μM; results have not been corrected for the endogenous levels
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Parasites & Vectors

ISSN: 1756-3305

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