Update on the distribution of Mansonella perstans in the southern part of Cameroon: influence of ecological factors and mass drug administration with ivermectin

Table 4 Percentage reduction in M. perstans prevalence and intensity in selected communities of Mamfe and Nwa surveyed before and under CDTI MDA

Regions	Bioecological zones	Health district	Prevalence (%)					Geometric mean
Regions	Bioecological zones	Health district	Before IVM MDA	Under IVM MDA	% reduction	χ ²	P-value	Before IVM MDA	Under IVM MDA	% reduction	P-value
South west	DERF	Mamfe	64.60	49.73	23.02	0.7529	0.335	2,957.8	1,934.8	34.58	< 0.0001
South west	DHERF	Mamfe	59.40	71.97	-21.16	10.6411	0.001	5,800.9	5,743.6	0.99	< 0.0001
North west	FS	Nwa	0.20	0.50	-150.00	0.0331	0.281	13.90	175.8	-1164.74	< 0.0001

Abbreviations: DERF deciduous equatorial rainforest, DHERF dense humid equatorial rainforest, FS forested savanna, IVM MDA ivermectin mass drug administration (χ ² test was used to compare prevalence rates before and under treatment; t-test was used to compare mean intensity of infection before and under treatment)

ISSN: 1756-3305